Chercheurs

Médecine / SIMON, CARLOS

csimonv

Position

Catedrático de Obstetricia y Ginecología
Especialidad: Ginecólogo

Director Científico, Instituto Valenciano de Infertilidad (IVI) y Fundación IVI desde 1994.

Director Científico del Centro de Investigación Príncipe Felipe (CIPF), 2009-2011. Director del Banco Nacional de Líneas Celulares, Nodo de Valencia situado en el CIPF, 2004 – 2011.

Presidente Asociación de Empresas de Biotecnología de la Comunidad Valenciana, BIOVAL desde 2009.

Thèmes de recherche

Desde hace 20 años el doctor Simón ha dirigido su actividad a la investigación médica aplicada en medicina reproductiva y medicina regenerativa.

Prix et récompenses

Premio Rey Jaime I, Investigación Médica 2011.
Premio a la Excelencia Científica en Educación Médica 2011. Serono Symposia International Foundation.
Galardonado por: Sociedad Española de Fertilidad (SEF) 1991, 2001 y 2003; Sociedad Española de Obs. y Gin. (SEGO) 1997 y 1999; Society for Gynecological Investigation (SGI) 1993, 2002 y 2009; American Society for Reproductive Medicine (ASRM) 1993, 1995, 1997, 1999, 2001, 2005, 2008 y 2011.
Premio Investigación Clínica, Fundación H. Clínico U.V, 2006.
5 Premios de la Fundación Salud 2000 (1996, 1999, 2001, 2005, 2010).
Premio Vicente Zaragozá Orts, Soc. Obs. y Gin. CV. 1995.
Premio López Sancho, UV. 1986. Premio Expectativas, Soc. Valen. Diabetes. 2005. Premio Investigación “2 primeras líneas de células madre en España”. M. I. Acad. Mund. Cien. Tecnol. Educ. y Human. 2004.
Premio Mejor artículo básico 2003, Revista Iberoamericana de Fertilidad.

Publications

Editor de 14 libros. Ha publicado 275 trabajos en revistas internacionales con un índice de impacto de 1.076,246 con un total de 7.038 citas recibidas y un promedio de citas/trabajo de 25,59. Su Factor h= 45.

Ha publicado 98 artículos en revistas nacionales.

Somatic stem cells in the human endometrium.
Cervelló I, Mas A, Gil-Sanchis C, Simón C.
Semin Reprod Med. 2013 Jan;31(1):69-76. doi: 10.1055/s-0032-1331800. Epub 2013 Jan 17. Review.
PMID: 23329639 [PubMed - indexed for MEDLINE]

Somatic stem cells in the endometrium.
Cervelló I, Simón C.
Reprod Sci. 2009 Feb;16(2):200-5. doi: 10.1177/1933719108329955. Review.
PMID: 19208788 [PubMed - indexed for MEDLINE]

Stem cells in human endometrium and endometrial carcinoma.
Cervelló I, Mirantes C, Santamaria X, Dolcet X, Matias-Guiu X, Simón C.
Int J Gynecol Pathol. 2011 Jul;30(4):317-27. doi: 10.1097/PGP.0b013e3182102754. Review.
PMID: 21623195 [PubMed - indexed for MEDLINE]

Human endometrial side population cells exhibit genotypic, phenotypic and functional features of somatic stem cells.
Cervelló I, Gil-Sanchis C, Mas A, Delgado-Rosas F, Martínez-Conejero JA, Galán A, Martínez-Romero A, Martínez S, Navarro I, Ferro J, Horcajadas JA, Esteban FJ, O\'Connor JE, Pellicer A, Simón C.
PLoS One. 2010 Jun 24;5(6):e10964. doi: 10.1371/journal.pone.0010964.
PMID: 20585575 [PubMed - indexed for MEDLINE] Free PMC Article

Leucine-rich repeat-containing G-protein-coupled receptor 5 (Lgr5) as a putative human endometrial stem cell marker.
Gil-Sanchis C, Cervelló I, Mas A, Faus A, Pellicer A, Simón C.
Mol Hum Reprod. 2013 Jul;19(7):407-14. doi: 10.1093/molehr/gat014. Epub 2013 Mar 7.
PMID: 23475985 [PubMed - indexed for MEDLINE]

Reconstruction of endometrium from human endometrial side population cell lines.
Cervelló I, Mas A, Gil-Sanchis C, Peris L, Faus A, Saunders PT, Critchley HO, Simón C.
PLoS One. 2011;6(6):e21221. doi: 10.1371/journal.pone.0021221. Epub 2011 Jun 21.
PMID: 21712999 [PubMed - indexed for MEDLINE] Free PMC Article

Bone marrow-derived cells from male donors do not contribute to the endometrial side population of the recipient.
Cervelló I, Gil-Sanchis C, Mas A, Faus A, Sanz J, Moscardó F, Higueras G, Sanz MA, Pellicer A, Simón C.
PLoS One. 2012;7(1):e30260. doi: 10.1371/journal.pone.0030260. Epub 2012 Jan 19.
PMID: 22276168 [PubMed - indexed for MEDLINE] Free PMC Article

Identification and characterization of the human leiomyoma side population as putative tumor-initiating cells.
Mas A, Cervelló I, Gil-Sanchis C, Faus A, Ferro J, Pellicer A, Simón C.
Fertil Steril. 2012 Sep;98(3):741-751.e6. doi: 10.1016/j.fertnstert.2012.04.044. Epub 2012 May 23.
PMID: 22633281 [PubMed - indexed for MEDLINE]

Identification, characterization and co-localization of label-retaining cell population in mouse endometrium with typical undifferentiated markers.
Cervelló I, Martínez-Conejero JA, Horcajadas JA, Pellicer A, Simón C.
Hum Reprod. 2007 Jan;22(1):45-51. Epub 2006 Aug 21.
PMID: 16923745 [PubMed - indexed for MEDLINE] Free Article

Cells, stem cells, and cancer stem cells.
Aguilar-Gallardo C, Simón C.
Semin Reprod Med. 2013 Jan;31(1):5-13. doi: 10.1055/s-0032-1331792. Epub 2013 Jan 17. Review.
PMID: 23329631 [PubMed - indexed for MEDLINE]

Stem cells helping reproductive medicine.
Simón C.
Semin Reprod Med. 2013 Jan;31(1):3-4. doi: 10.1055/s-0032-1331791. Epub 2013 Jan 17. No abstract available.
PMID: 23329630 [PubMed - indexed for MEDLINE]

Tissue-derived mesenchymal stromal cells used as vehicles for anti-tumor therapy exert different in vivo effects on migration capacity and tumor growth.
Belmar-Lopez C, Mendoza G, Oberg D, Burnet J, Simon C, Cervello I, Iglesias M, Ramirez JC, Lopez-Larrubia P, Quintanilla M, Martin-Duque P.
BMC Med. 2013 May 28;11:139. doi: 10.1186/1741-7015-11-139.
PMID: 23710709 [PubMed - indexed for MEDLINE] Free PMC Article

Germ cell differentiation from pluripotent cells.
Medrano JV, Pera RA, Simón C.
Semin Reprod Med. 2013 Jan;31(1):14-23. doi: 10.1055/s-0032-1331793. Epub 2013 Jan 17. Review.
PMID: 23329632 [PubMed - indexed for MEDLINE]

Somatic stem cells and tissue engineering shed light on unsolved clinical issues in reproductive medicine: in stem cells we trust.
Simón C.
Fertil Steril. 2012 Jul;98(1):1-2. doi: 10.1016/j.fertnstert.2012.05.021. Epub 2012 May 31.
PMID: 22658346 [PubMed - indexed for MEDLINE]

Uterine and ovarian function in endometriosis.
Garrido N, Pellicer A, Remohí J, Simón C.
Semin Reprod Med. 2003 May;21(2):183-92. Review.
PMID: 12917788 [PubMed - indexed for MEDLINE]

Uterine receptivity and the ramifications of ovarian stimulation on endometrial function.
Horcajadas JA, Díaz-Gimeno P, Pellicer A, Simón C.
Semin Reprod Med. 2007 Nov;25(6):454-60. Review.
PMID: 17960530 [PubMed - indexed for MEDLINE]

Physiology and pathology of ovarian hyperstimulation syndrome.
Gómez R, Soares SR, Busso C, Garcia-Velasco JA, Simón C, Pellicer A.
Semin Reprod Med. 2010 Nov;28(6):448-57. doi: 10.1055/s-0030-1265670. Epub 2010 Nov 16. Review.
PMID: 21082502 [PubMed - indexed for MEDLINE]

Derivation of clinical-grade human embryonic stem cells.
Rodríguez CI, Galán A, Valbuena D, Simón C.
Reprod Biomed Online. 2006 Jan;12(1):112-8. Review.
PMID: 16454945 [PubMed - indexed for MEDLINE]

Controlled ovarian stimulation induces a functional genomic delay of the endometrium with potential clinical implications.
Horcajadas JA, Mínguez P, Dopazo J, Esteban FJ, Domínguez F, Giudice LC, Pellicer A, Simón C.
J Clin Endocrinol Metab. 2008 Nov;93(11):4500-10. doi: 10.1210/jc.2008-0588. Epub 2008 Aug 12.
PMID: 18697870 [PubMed - indexed for MEDLINE]

First derivation in Spain of human embryonic stem cell lines: use of long-term cryopreserved embryos and animal-free conditions.
Simón C, Escobedo C, Valbuena D, Genbacev O, Galan A, Krtolica A, Asensi A, Sánchez E, Esplugues J, Fisher S, Pellicer A.
Fertil Steril. 2005 Jan;83(1):246-9.
PMID: 15652923 [PubMed - indexed for MEDLINE]