Chercheurs

Technologie / SCHIEVANO, SILVIA

s.schievano(at)

Position

RAEng/EPSRC Research Fellow, UCL Institute of Child Health & Great Ormond Street Hospital for Children, London, UK.

Thèmes de recherche

Biomedical engineer Dr Silvia Schievano has pioneered the development of patient-specific heart valves that can be implanted into the heart without surgery, triggering what cardiologists describe as a paradigm shift in how they approach the clinical challenges they meet in replacing pulmonary valves.

Prix et récompenses

In 2009, Dr Schievano won the Sir George MacFarlane Medal from the Academy for excellence in the early stage of an engineering career.

Publications

2013

diaz-zuccarini, V., & Schievano, S. (2013). Biomedical Imaging And Computational Modeling In Cardiovascular Disease: Patient-Specific Applications Using Numerical Models. In D. Iacovello, U. Andreaus (Eds.), Biomedical Imaging and Computational Modeling in Biomechanics. Springer.

Biglino, G., Giardini, A., Baker, C., Figliola, R. S., Hsia, T. Y., Taylor, A. M., . . . and MOCHA Collaborative Group. (2013). Implementing the Sano Modification in an Experimental Model of First-stage Palliation of Hypoplastic Left Heart Syndrome. ASAIO J, 59 (1), 86-89. doi:10.1097/MAT.0b013e3182768b7f

Schievano, S., taylor, A., & bonhoeffer, P. (2013). Percutaneous pulmonary valve implantation: the first transcatheter valve. In P. A. Iazzo, R. W. Bianco, A. J. Hill, J. D. St Louis (Eds.), Heart Valves: From Design to Clinical Implantation.

2012

Bhattacharya-Ghosh, B, Schievano, S, & Diaz, V. (2012). A multi-physics and multi-scale lumped parameter model of cardiac contraction of the left ventricle: A conceptual model from the protein to the organ scale. Computers in Biology and Medicine, 42 (10), 982-992. doi:10.1016/j.compbiomed.2012.07.010

Biglino, G., Steeden, J. A., Baker, C., Schievano, S., Taylor, A. M., Parker, K. H., & Muthurangu, V. (2012). A non-invasive clinical application of wave intensity analysis based on ultrahigh temporal resolution phase-contrast cardiovascular magnetic resonance. J Cardiovasc Magn Reson, 14, 57-?. doi:10.1186/1532-429X-14-57

Schievano, S., Capelli, C., Cosentino, D., Bosi, G., & Taylor, A. M. (2012). Finite Element Analysis to Study Percutaneous Heart Valves. In D. Moratal (Ed.), Finite Element Analysis (pp. 167-174). Intech. doi:10.5772/38701

Capelli, C., Biglino, G., Petrini, L., Migliavacca, F., Cosentino, D., Bonhoeffer, P., . . . Schievano, S. (2012). Finite element strategies to satisfy clinical and engineering requirements in the field of percutaneous valves. Ann Biomed Eng, 40 (12), 2663-2673. doi:10.1007/s10439-012-0617-1

Lurz, P., Muthurangu, V., Schuler, P. K., Giardini, A., Schievano, S., Nordmeyer, J., . . . Taylor, A. M. (2012). Impact of reduction in right ventricular pressure and/or volume overload by percutaneous pulmonary valve implantation on biventricular response to exercise: an exercise stress real-time CMR study. Eur Heart J, 33 (19), 2434-2441. doi:10.1093/eurheartj/ehs200

Biglino, G., Giardini, A., Baker, C., Figliola, R. S., Hsia, T. Y., Taylor, A. M., . . . MOCHA Collaborative Group. (2012). In vitro study of the Norwood palliation: a patient-specific mock circulatory system. ASAIO J, 58 (1), 25-31. doi:10.1097/MAT.0b013e3182396847

Capelli, C., Bosi, G. M., Cerri, E., Nordmeyer, J., Odenwald, T., Bonhoeffer, P., . . . Schievano, S. (2012). Patient-specific simulations of transcatheter aortic valve stent implantation. Med Biol Eng Comput, 50 (2), 183-192. doi:10.1007/s11517-012-0864-1

Biglino, G., Schievano, S., Muthurangu, V., & Taylor, A. M. (2012). Perspectives in cardiac modelling. In J. Bogaert, S. Dymarkowsky, A. M. Taylor, V. Muthurangu (Eds.), Clinical cardiac MRI (pp. 669-694). Springer.

Kung, E., Baretta, A., Baker, C., Arbia, G., Biglino, G., Corsini, C., . . . for the Modeling Of Congenital Hearts Alliance (MOCHA)+ Investigators. (2012). Predictive modeling of the virtual Hemi-Fontan operation for second stage single ventricle palliation: Two patient-specific cases. J Biomech. doi:10.1016/j.jbiomech.2012.10.023

Biglino, G., Schievano, S., Steeden, J. A., Ntsinjana, H., Baker, C., Khambadkone, S., . . . Giardini, A. (2012). Reduced ascending aorta distensibility relates to adverse ventricular mechanics in patients with hypoplastic left heart syndrome: Noninvasive study using wave intensity analysis. Journal of Thoracic and Cardiovascular Surgery, 144 (6), 1307-1314.

Biglino, G., Schievano, S., Steeden, J. A., Ntsinjana, H., Baker, C., Khambadkone, S., . . . Modeling of Congenital Hearts Alliance (MOCHA) Collaborative Group. (2012). Reduced ascending aorta distensibility relates to adverse ventricular mechanics in patients with hypoplastic left heart syndrome: Noninvasive study using wave intensity analysis. J Thorac Cardiovasc Surg, 144 (6), 1307-1314. doi:10.1016/j.jtcvs.2012.08.028

Quail, M. A., Nordmeyer, J., Schievano, S., Reinthaler, M., Mullen, M. J., & Taylor, A. M. (2012). Use of cardiovascular magnetic resonance imaging for TAVR assessment in patients with bioprosthetic aortic valves: Comparison with computed tomography. European Journal of Radiology, 81 (12), 3912-3917.

Quail, M. A., Nordmeyer, J., Schievano, S., Reinthaler, M., Mullen, M. J., & Taylor, A. M. (2012). Use of cardiovascular magnetic resonance imaging for TAVR assessment in patients with bioprosthetic aortic valves: Comparison with computed tomography. European Journal of Radiology, 81 (12), 3912-3917.
doi:10.1016/j.ejrad.2012.07.014

Biglino, G., Capelli, C., Binazzi, A., Reggiani, R., Cosentino, D., Migliavacca, F., . . . Schievano, S. (2012). Virtual and real bench testing of a new percutaneous valve device: a case study. EuroIntervention, 8 (1), 120-128. doi:10.4244/EIJV8I1A19

2011

Lurz, P., Nordmeyer, J., Giardini, A., Khambadkone, S., Muthurangu, V., Schievano, S., . . . Bonhoeffer, P. (2011). Early versus late functional outcome after successful percutaneous pulmonary valve implantation: are the acute effects of altered right ventricular loading all we can expect?. J Am Coll Cardiol, 57 (6), 724-731. doi:10.1016/j.jacc.2010.07.056

Schievano, S., Capelli, C., Young, C., Lurz, P., Nordmeyer, J., Owens, C., . . . Taylor, A. M. (2011). Four-dimensional computed tomography: a method of assessing right ventricular outflow tract and pulmonary artery deformations throughout the cardiac cycle. Eur Radiol, 21 (1), 36-45. doi:10.1007/s00330-010-1913-5

Moledina, S., de Bruyn, A., Schievano, S., Owens, C. M., Young, C., Haworth, S. G., . . . Muthurangu, V. (2011). Fractal branching quantifies vascular changes and predicts survival in pulmonary hypertension: a proof of principle study. Heart, 97 (15), 1245-1249. doi:10.1136/hrt.2010.214130

Migliavacca, F., Baker, C., Biglino, G., Bosi, G., Capelli, C., Cerri, E., . . . SCHIEVANO, S. (2011). Numerical simulations to study aortic arch pathologies: application to hypoplastic left heart syndrome, aortic coarctation and aortic valve diseases. New endovascular technologies: from bench test to clinical practice. (pp. 9-22).

Nordmeyer, J., Lurz, P., Khambadkone, S., Schievano, S., Jones, A., McElhinney, D. B., . . . Bonhoeffer, P. (2011). Pre-stenting with a bare metal stent before percutaneous pulmonary valve implantation: acute and 1-year outcomes. Heart, 97 (2), 118-123. doi:10.1136/hrt.2010.198382

Biglino, G., Schievano, S., & Taylor, A. M. (2011). The use of rapid prototyping in clinical applications. In M. E. Hoque (Ed.), Rapid Prototyping / Book 2.

2010

Schievano, S., Capelli, C., Taylor, A. M., & Bonhoeffer, P. (2010). Application of computational simulations for percutaneous pulmonary valve implantation. (Percutaneous pulmonary valve computer analysis). Progress in Pediatric Cardiology, 30 (1-2), 15-21.

Vitanovski, D., Tsymbal, A., Ionasec, R. I., Georgescu, B., Hubert, M., Taylor, A., . . . Comaniciu, D. (2010). Cross-modality assessment and planning for pulmonary trunk treatment using CT and MRI imaging. Med Image Comput Comput Assist Interv, 13 (Pt 1), 460-467.

Lurz, P., Giardini, A., Taylor, A. M., Nordmeyer, J., Muthurangu, V., Odendaal, D., . . . Derrick, G. (2010). Effect of altering pathologic right ventricular loading conditions by percutaneous pulmonary valve implantation on exercise capacity. Am J Cardiol, 105 (5), 721-726. doi:10.1016/j.amjcard.2009.10.054

Schievano, S., Taylor, A. M., Capelli, C., Coats, L., Walker, F., Lurz, P., . . . Bonhoeffer, P. (2010). First-in-man implantation of a novel percutaneous valve: a new approach to medical device development. EuroIntervention, 5 (6), 745-750.

Capelli, C., Nordmeyer, J., Schievano, S., Lurz, P., Khambadkone, S., Lattanzio, S., . . . Bonhoeffer, P. (2010). How do angioplasty balloons work: a computational study on balloon expansion forces. EuroIntervention, 6 (5), 638-642. doi:10.4244/EIJV6I5A106

Schievano, S., Taylor, A. M., Capelli, C., Lurz, P., Nordmeyer, J., Migliavacca, F., & Bonhoeffer, P. (2010). Patient specific finite element analysis results in more accurate prediction of stent fractures: Application to percutaneous pulmonary valve implantation. Journal of Biomechanics, 43 (4), 687-693.

Capelli, C., Taylor, A. M., Migliavacca, F., Bonhoeffer, P., & Schievano, S. (2010). Patient-specific reconstructed anatomies and computer simulations are fundamental for selecting medical device treatment: application to a new percutaneous pulmonary valve. Philos Transact A Math Phys Eng Sci, 368 (1921), 3027-3038. doi:10.1098/rsta.2010.0088

SCHIEVANO, S., SEBIRE, N., ROBERTSON, N., TAYLOR, A., & THAYYIL, S. (2010). Reconstruction of fetal and infant anatomy using rapid prototyping of post-mortem MR images. Insights Imaging, 1 (4), 281-286. doi:10.1007/s13244-010-0028-5