Centre International de Recherche Scientifique
dbruns![]()
Professor of Pathology, Director of Clinical Chemistry and Toxicology, Associate Director of Molecular Diagnostics Laboratory, Department of Pathology, University of Virginia, USA.
* Quality requirements for medical tests
* Harmonization of laboratory tests
Dr. Bruns has worked in clinical enzymology, toxicology, calcium-regulating hormones, and evidence-based laboratory medicine.
Dr. Bruns has been President of the Academy of Clinical Laboratory Physicians and Scientists and the Association of Clinical Scientists. He received the AACC Award for Research in a Selected Area (1987) and Outstanding Contributions to Clinical Chemistry (1998).
RECENT BOOKS
Bruns DE, Ashwood ER, Burtis CA, eds. Fundamentals of Molecular Diagnostics. St. Louis: Saunders/Elsevier, 2007.
Burtis CA, Ashwood ER, Bruns DE, eds. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 5th ed., St. Louis: Saunders/Elsevier, 2012.
Burtis CA, Bruns DE, eds. Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics. 7th ed. St. Louis: Saunders/Elsevier, 2015
SELECTED REFERENCES
Bossuyt PM, Reitsma JB, Bruns DE, Gatsonis CA, Glasziou PP, Irwig LM, Lijmer JG, Moher D, Rennie D, DeVet HC. Towards complete and accurate reporting of studies of diagnostic accuracy: The STARD Initiative. Ann Intern Med 2003; 138:40-44 (and 14 other journals).
Sacks, DB, Arnold A, Bakris GL, Bruns DE, Horvath AR, Kirkman SK , Lernmark A, Metzger BE , Nathan DM. Executive summary: guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Clin Chem 2011;57:793-8 and Diabetes Care 2011;34:1419-23.
Sacks DB, Bruns DE, Horton J, Lindberg S, Mahoney JJ, Manzella S, Reilly ET, Scott MG. Point-of-care blood glucose testing in acute and chronic care facilities: approved guideline. Clinical Laboratory Standards Institute 2013;33:1-48.
Algeciras-Schimnich A, Bruns DE, Boyd JC, Bryant S, La Fortune KA, Grebe SKG. Failure of current laboratory protocols to detect lot-to-lot reagent differences: Findings and possible solutions. Clin Chem 2013;59:1187-94. (Related Editorial: Bennett ST. Clin Chem 2013;59:1145-7).
Kelly BN, Haverstick DM, Lee JK, Thorner MO, Vance ML, Xin W, Bruns DE. Circulating microRNA as a biomarker of human growth hormone administration to patients. Drug Test Anal 2014;6:234-8.
Mitsios JV, Ashby LA, Haverstick DM, Bruns DE, Scott MG. Analytic evaluation of a new glucose meter system in 15 different critical care settings. Diabetes Sci Technol 2013;7:1282-7.
Bachmann LM, Nilsson G, Bruns DE, McQueen MJ, Lieske JC, Zakowski JJ, Miller WG. State of the art for measurement of urine albumin: comparison of routine measurement procedures to isotope dilution tandem mass spectrometry. Clin Chem 2014;60:471-80. (Related Editorial: Scott MG, Coyne DW. Clin Chem 2014;60:435-7.)
Boyd JC, Bruns DE. Effects of measurement frequency on analytical quality required for glucose measurements in ICUs: assessments by simulation models. Clin Chem 2014;60:644-50. (Related Editorial: Van den Berghe G. Clin Chem 2014;60:577-9).
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