Retina specialist at the Massachusetts Eye and Ear Infirmary (MEEI) and Harvard Medical School (HMS),
Professor of Ophthalmology,
Henry Willard Williams Professor of Ophthalmology at MEEI and Chairman of Ophthalmology at HMS.
Dr. Miller’s research interests are focused on ocular neovascularization, particularly as it relates to macular degeneration and diabetic retinopathy, including the role of growth factors, the development of anti-angiogenic therapy, and photodynamic therapy. She, along with Evangelos Gragoudas, M.D. pioneered the development of photodynamic therapy for neovascular macular degeneration. In addition, Dr. Miller and her colleagues were among the first to demonstrate the importance of a growth factor, vascular endothelial growth factor (VEGF) in the development of ocular neovascularization and the potential use of drug therapies targeting VEGF.
She has received numerous awards, including the Rosenthal Award of the Macula Society, the Retina Research Award from the Club Jules Gonin and the Alcon Research Institute Award.
Professional Affiliations :
American Academy of Ophthalmology, Association for Research in Vision and Ophthalmology, Inc. (ARVO), The New England Ophthalmological Society (NEOS)
Poulaki V, Iliaki E, Mitsiades N, Mitsiades CS, Mantas YP, Bula DV, Gragoudas ES, Miller JW.
Abstract Inhibition of Hsp90 attenuates inflammation in endotoxin-induced uveitis.
FASEB J. 2007 Mar 30;
Miller KJ, Leuthardt EC, Schalk G, Rao RP, Anderson NR, Moran DW, Miller JW, Ojemann JG.
Spectral changes in cortical surface potentials during motor movement.
J Neurosci. 2007 Feb 28;27(9):2424-32.
Are Ictal Fast Ripples an \"Electronic Signature\" for the Seizure-onset Zone?
Epilepsy Curr. 2007 Jan-Feb;7(1):7-9.
Kalayoglu MV, Miller JW.
Infection, inflammation and age-related macular degeneration.
Clin Experiment Ophthalmol. 2007 Jan-Feb;35(1):3-4.
Haan MN, Miller JW, Aiello AE, Whitmer RA, Jagust WJ, Mungas DM, Allen LH, Green R.
Homocysteine, B vitamins, and the incidence of dementia and cognitive impairment: results from the Sacramento Area Latino Study on Aging.
Am J Clin Nutr. 2007 Feb;85(2):511-7.
Nakazawa T, Hisatomi T, Nakazawa C, Noda K, Maruyama K, She H, Matsubara A, Miyahara S, Nakao S, Yin Y, Benowitz L, Hafezi-Moghadam A, Miller JW.
Monocyte chemoattractant protein 1 mediates retinal detachment-induced photoreceptor apoptosis.
Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2425-30. Epub 2007 Feb 6.
Miller JW, Kim W, Holmes MD, Vanhatalo S.
Ictal localization by source analysis of infraslow activity in DC-coupled scalp EEG recordings.
Neuroimage. 2007 Apr 1;35(2):583-97. Epub 2006 Dec 23.
Long-term outcomes of childhood epilepsy: \"the truth is rarely pure and never simple\".
Epilepsy Curr. 2006 Nov-Dec;6(6):181-3.
Pachydaki S, Sobrin L, Miller JW.
Photodynamic therapy and combination treatments.
Int Ophthalmol Clin. 2007 Winter;47(1):95-115. Review.
DeAngelis MM, Ji F, Kim IK, Adams S, Capone A Jr, Ott J, Miller JW, Dryja TP.
Abstract Cigarette smoking, CFH, APOE, ELOVL4, and risk of neovascular age-related macular degeneration.
Arch Ophthalmol. 2007 Jan;125(1):49-54.
Hafezi-Moghadam A, Noda K, Almulki L, Iliaki EF, Poulaki V, Thomas KL, Nakazawa T, Hisatomi T, Miller JW, Gragoudas ES.
VLA-4 blockade suppresses endotoxin-induced uveitis: in vivo evidence for functional integrin up-regulation.
FASEB J. 2007 Feb;21(2):464-74. Epub 2007 Jan 3.